Molecularly imprinted polymer-capped nitrogen-doped graphene quantum dots as a novel chemiluminescence sensor for selective and sensitive determination of doxorubicin
作者： Mohammad Amjadi , Roghayeh Jalili
DOI: 10.1039/C6RA18184H
关键词:
摘要: In this work, molecularly imprinted polymer-capped nitrogen-doped graphene quantum dots (MIP@NGQDs) were prepared via a simple sol–gel process and used for recognition of the anti-cancer drug, doxorubicin. Strong chemiluminescence (CL) emission was observed when potassium permanganate injected into solution MIP@NGQDs. At same time, in presence doxorubicin CL intensity significantly quenched exploited to develop detection scheme drug. The mechanism MIP@NGQDs/KMnO4 system investigated by recording UV-Vis, fluorescence spectra. Under optimal conditions, relative linearly decreased with concentration range 20–260 μg L−1. limit 4.7 method applied determination therapeutic levels spiked serum samples satisfactory results.
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