Ultrasound-detected carotid plaque as a screening tool for advanced subclinical atherosclerosis.

作者: Rachael A. Wyman , Michael C. Fraizer , Jon G. Keevil , Kjersten L. Busse , Susan E. Aeschlimann

DOI: 10.1016/J.AHJ.2005.01.010

关键词:

摘要: Background There is great need for a simple, noninvasive tool that can be used in an office setting to screen subclinical atherosclerosis. In patients referred cardiovascular (CV) risk assessment, we evaluated the ability of ultrasound screening carotid plaque identify with advanced Methods Consecutive asymptomatic without vascular disease by their physician measurement ankle-brachial pressure index and intima-media thickness (CIMT) were included. Carotid was measured using standardized protocol from Atherosclerosis Risk Communities (ARIC) study. Advanced atherosclerosis defined as CIMT ≥75th percentile age, sex, race ARIC. Results The mean age 327 subjects 55.4 years (SD 7.7 years). 10-year Framingham CV 5.1% (4.8%). multiple logistic regression model included risk, index, use lipid-lowering medications, presence significantly predicted (odds ratio 3.08, 95% CI 1.91-4.96, P Conclusion Ultrasound detection helped Screening easier than determination may help detect at increased risk.

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