Challenge of Thrombolytic Therapy in Unstable Angina Pectoris

作者: John A. Venditto , John A. Ambrose

DOI: 10.1007/978-1-4615-2628-5_19

关键词:

摘要: The central role of thrombosis in acute coronary syndromes has been recognized for over a century. Parkinson and Bedford, 1928, noted that myocardial infarction was the result “final occlusion arteries due to at site constriction or ulceration vessel” (1). Disruption an atherosclerotic plaque with thrombus formation is proven substrate development majority patients presenting ST-segment elevation (2, 3, 4). Understanding importance intracoronary led first published trial thrombolytic therapy more than 30 years ago (5).

参考文章(111)
J J Badimon, J H Chesebro, L Badimon, Thrombus formation on ruptured atherosclerotic plaques and rethrombosis on evolving thrombi. Circulation. ,vol. 86, ,(1992)
J. A. Ambrose, Coronary Angiographic Findings in the Acute Coronary Syndromes Springer, Berlin, Heidelberg. pp. 112- 128 ,(1990) , 10.1007/978-3-642-61288-6_8
B Adelman, A Rizk, E Hanners, Plasminogen interactions with platelets in plasma Blood. ,vol. 72, pp. 1530- 1535 ,(1988) , 10.1182/BLOOD.V72.5.1530.1530
W M O'Fallon, J F Keane, D J Driscoll, D R Pieroni, C J Hayes, W M Gersony, L Kidd, R R Wolfe, W H Weidman, Second natural history study of congenital heart defects. Results of treatment of patients with ventricular septal defects Circulation. ,vol. 87, pp. 38- ,(1993)
Valentin Fuster, Marc Verstraete, Thrombosis in Cardiovascular Disorders ,(1992)
C Bode, M S Runge, E E Branscomb, J B Newell, G R Matsueda, E Haber, Antibody-directed fibrinolysis. An antibody specific for both fibrin and tissue plasminogen activator. Journal of Biological Chemistry. ,vol. 264, pp. 944- 948 ,(1989) , 10.1016/S0021-9258(19)85034-2
Dimitrios Alexopoulos, John A. Ambrose, David Stump, Susan Borrico, Richard Gorlin, Prammod Deshmuck, Edward A. Fisher, Thrombosis-related markes in unstable angina pectoris Journal of the American College of Cardiology. ,vol. 17, pp. 866- 871 ,(1991) , 10.1016/0735-1097(91)90867-9
E Falk, Why do plaques rupture Circulation. ,vol. 86, ,(1992)