Missed Opportunities to Initiate Oral Anticoagulant in Atrial Fibrillation: Insights from Australian Acute Coronary Syndrome Registries

作者: David Brieger , Derek Chew , Karice Hyun , Miles Ma , Mario D'Souza

DOI: 10.1016/J.HLC.2021.01.005

关键词:

摘要: Background Many patients with atrial fibrillation (AF) do not receive oral anticoagulant (OAC) therapy. The aims of this study were to 1) document receipt OAC among a history AF admitted an acute coronary syndrome (ACS); and 2) determine whether hospital admission was associated improvement in prescription Methods Using Australian data from the Cooperative National Registry Acute Coronary Care, Guideline Adherence Clinical Events (CONCORDANCE) Global (GRACE) registries, 1,479 presenting ACS separated into two groups: aspirin monotherapy/no therapy (No OAC) or ± (OAC). characteristics in-hospital treatments outcomes compared. Results Of patients, 532 (36%) presented on remainder receiving antiplatelet (n=580 [39%]) no antithrombotic (n=367 [25%]). Treatment prior presentation increased during 18 years (27% 56%, p=0.0002). Ninety-five per cent (95%) group had CHA2DS2-VA score >1 vs 88% No (p Conclusion In AF, has improved over time but remains suboptimal. There is minimal escalation provision care, indicating missed opportunities address evidence practice gap.

参考文章(36)
Robby Nieuwlaat, Nancy Wilczynski, Tamara Navarro, Nicholas Hobson, Rebecca Jeffery, Arun Keepanasseril, Thomas Agoritsas, Niraj Mistry, Alfonso Iorio, Susan Jack, Bhairavi Sivaramalingam, Emma Iserman, Reem A Mustafa, Dawn Jedraszewski, Chris Cotoi, R. Brian Haynes, Interventions for enhancing medication adherence. Cochrane Database of Systematic Reviews. ,vol. 2014, ,(2008) , 10.1002/14651858.CD000011.PUB4
B. Aliprandi-Costa, I. Ranasinghe, F. Turnbull, A. Brown, L. Kritharides, A. Patel, D. Chew, D. Walters, J. Rankin, M. Ilton, I. Meredith, A. Cass, D. Brieger, The Design and Rationale of the Australian Cooperative National Registry of Acute Coronary care, Guideline Adherence and Clinical Events (CONCORDANCE) Heart Lung and Circulation. ,vol. 22, pp. 533- 541 ,(2013) , 10.1016/J.HLC.2012.12.013
Gregory Y.H. Lip, Cécile Laroche, Gheorghe-Andrei Dan, Massimo Santini, Zbigniew Kalarus, Lars Hvilsted Rasmussen, Popescu Mircea Ioachim, Otilia Tica, Giuseppe Boriani, Paolo Cimaglia, Igor Diemberger, Camilla Fragtrup Hellum, Bettina Mortensen, Aldo P. Maggioni, ‘Real-World’ Antithrombotic Treatment in Atrial Fibrillation: The EORP-AF Pilot Survey The American Journal of Medicine. ,vol. 127, pp. 519- 529.e1 ,(2014) , 10.1016/J.AMJMED.2013.12.022
S. Ben Freedman, B. J. Gersh, G. Y. H. Lip, Misperceptions of aspirin efficacy and safety may perpetuate anticoagulant underutilization in atrial fibrillation European Heart Journal. ,vol. 36, pp. 653- 656 ,(2015) , 10.1093/EURHEARTJ/EHU494
Renato D. Lopes, Li Li, Christopher B. Granger, Tracy Y. Wang, JoAnne M. Foody, Marjorie Funk, Eric D. Peterson, Karen P. Alexander, Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes. The American Journal of Medicine. ,vol. 125, pp. 897- 905 ,(2012) , 10.1016/J.AMJMED.2012.04.006
Hani Amad, Andrew T Yan, Raymond T Yan, Thao Huynh, Joel M Gore, Gilles Montalescot, J Paul DeYoung, Richard Gallo, Barry Rose, P Gabriel Steg, Shaun G Goodman, Canadian Global Registry of Acute Coronary Events (GRACE) Investigators, The Association Between Prior Use of Aspirin and/or Warfarin and the In-hospital Management and Outcomes in Patients Presenting With Acute Coronary Syndromes: Insights From the Global Registry of Acute Coronary Events (GRACE) Canadian Journal of Cardiology. ,vol. 28, pp. 48- 53 ,(2012) , 10.1016/J.CJCA.2011.09.003
Derek P Chew, Craig Juergens, John French, Will Parsonage, Matthew Horsfall, David Brieger, Stephen Quinn, Predict Study Investigators, An examination of clinical intuition in risk assessment among acute coronary syndromes patients: Observations from a prospective multi-center international observational registry International Journal of Cardiology. ,vol. 171, pp. 209- 216 ,(2014) , 10.1016/J.IJCARD.2013.12.010
Brian F. Gage, Amy D. Waterman, William Shannon, Michael Boechler, Michael W. Rich, Martha J. Radford, Validation of Clinical Classification Schemes for Predicting Stroke JAMA. ,vol. 285, pp. 2864- 2870 ,(2001) , 10.1001/JAMA.285.22.2864
Faisal Rahman, Gene F. Kwan, Emelia J. Benjamin, Global epidemiology of atrial fibrillation Nature Reviews Cardiology. ,vol. 11, pp. 639- 654 ,(2014) , 10.1038/NRCARDIO.2014.118