Assembly algorithms for next-generation sequencing data.

作者: Jason R. Miller , Sergey Koren , Granger Sutton

DOI: 10.1016/J.YGENO.2010.03.001

关键词:

摘要: The emergence of next-generation sequencing platforms led to resurgence research in whole-genome shotgun assembly algorithms and software. DNA data from the Roche 454, Illumina/Solexa, ABI SOLiD typically present shorter read lengths, higher coverage, different error profiles compared with Sanger data. Since 2005, several software packages have been created or revised specifically for de novo This review summarizes compares published descriptions named SSAKE, SHARCGS, VCAKE, Newbler, Celera Assembler, Euler, Velvet, ABySS, AllPaths, SOAPdenovo. More generally, it two standard methods known as Bruijn graph approach overlap/layout/consensus assembly.

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