Autoimmune hemolytic anemia as a paraneoplastic phenomenon in solid tumors: A critical analysis of 52 cases reported in the literature

摘要: Autoimmune hemolytic anemia (AIHA) is a well known paraneoplastic phenomenon in lymphoproliferative disorders but there are also number of case reports such an association with solid tumors. We have analysed 52 cases this reported the literature. found that AIHA may occur prior to, concurrent cancer or after end treatment, either as sign recurrence complete remission cancer. 70% patients had warm antibody and 30% cold AIHA. Some additional antibodies platelet (Evans syndrome), lupus anticoagulants to C1 esterase inhibitor. occurred almost all types cancers, it was relatively more common renal cell Kaposi sarcoma compared other cancers. In early stage particular curative resection cancers led complete, often sustained within short time patients. Resection tumor beneficial effects some metastatic Patients who response were refractory steroid treatment before surgery, while responses steroids observed The study autoimmune diseases provide important insights into biology