CLINICAL TRIALS:Gene Therapy Death Prompts Review of Adenovirus Vector

摘要: For the past 3 months, faculty and staff members at University of Pennsylvania9s Institute for Human Gene Therapy have been trying to understand why a relatively fit 18-year-old with an inherited enzyme deficiency died on 17 September, 4 days after doctors Penn injected genetically altered virus into his liver. Last week, they presented their data government advisory committee. The patient was first in gene therapy trial die itself; death is latest blow field that has struggling live up promise hype surrounding trials decade ago.