Toxin A of Clostridium difficile is a potent cytotoxin.

摘要: Clostridium difficile is the cause of antibiotic-associated colitis in humans. The organism produces toxin A, which generally known as enterotoxin, and B, cytotoxin. Toxin A has been reported to have slight cytotoxic activity; this study we show that cell lines (F9, OTF9-63, P19) express a carbohydrate binds are more sensitive toxin. These can be used research tools for determining concentrations biologically active should also prove useful studies mechanism action