Towards the preparation of radiolabeled 1-aryl-3-benzyl ureas: Radiosynthesis of [11C-carbonyl] AR-A014418 by [11C]CO2 fixation
作者： Justin W. Hicks , Alan A. Wilson , Elizabeth A. Rubie , James R. Woodgett , Sylvain Houle
DOI: 10.1016/J.BMCL.2011.12.139
关键词:
摘要: … )-N′-(5-nitro-1,3-thiazol-2-yl)urea (AR-A014418) was radiolabeled with carbon-11 ( 11 C; half-life=20.4min) at the urea moiety via [ 11 C]CO 2 fixation. Reaction of [ 11 C]CO 2 with 4-…
elsevier.com
sci-hub.se 参考文章(24)
Claudie Hooper, Richard Killick, Simon Lovestone, The GSK3 hypothesis of Alzheimer's disease. Journal of Neurochemistry. ,vol. 104, pp. 1433- 1439 ,(2008) , 10.1111/J.1471-4159.2007.05194.X
Alan A. Wilson, Armando Garcia, Sylvain Houle, Neil Vasdev, Direct fixation of [11C]-CO2 by amines: formation of [11C-carbonyl]-methylcarbamates Organic and Biomolecular Chemistry. ,vol. 8, pp. 428- 432 ,(2010) , 10.1039/B916419G
Sheelagh FRAME, Philip COHEN, GSK3 takes centre stage more than 20 years after its discovery. Biochemical Journal. ,vol. 359, pp. 1- 16 ,(2001) , 10.1042/0264-6021:3590001
Min Wang, Mingzhang Gao, Kathy D. Miller, George W. Sledge, Gary D. Hutchins, Qi-Huang Zheng, The first synthesis of [11C]SB-216763, a new potential PET agent for imaging of glycogen synthase kinase-3 (GSK-3) Bioorganic & Medicinal Chemistry Letters. ,vol. 21, pp. 245- 249 ,(2011) , 10.1016/J.BMCL.2010.11.026
S Vadivelan, Barij Nayan Sinha, Sunita Tajne, Sarma ARP Jagarlapudi, Fragment and knowledge-based design of selective GSK-3β inhibitors using virtual screening models European Journal of Medicinal Chemistry. ,vol. 44, pp. 2361- 2371 ,(2009) , 10.1016/J.EJMECH.2008.08.012
Neil Vasdev, Oleg Sadovski, Armando Garcia, Frédéric Dollé, Jeffrey H. Meyer, Sylvain Houle, Alan A. Wilson, Radiosynthesis of [11C]SL25.1188 via [11C]CO2 fixation for imaging monoamine oxidase B Journal of Labelled Compounds and Radiopharmaceuticals. ,vol. 54, pp. 678- 680 ,(2011) , 10.1002/JLCR.1908
Neil Vasdev, Armando Garcia, Winston T. Stableford, Alex B. Young, Jeffrey H. Meyer, Sylvain Houle, Alan A. Wilson, Synthesis and ex vivo evaluation of carbon-11 labelled N-(4-methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea ([11C]AR-A014418): A radiolabelled glycogen synthase kinase-3β specific inhibitor for PET studies Bioorganic & Medicinal Chemistry Letters. ,vol. 15, pp. 5270- 5273 ,(2005) , 10.1016/J.BMCL.2005.08.037
Dennis C. Dean, Michael A. Wallace, Tina M. Marks, David G. Melillo, Efficient utilization of [14C]carbon dioxide as a phosgene equivalent for labeled synthesis Tetrahedron Letters. ,vol. 38, pp. 919- 922 ,(1997) , 10.1016/S0040-4039(96)02513-0
Rodrigo Machado-Vieira, Giacomo Salvadore, Nancy DiazGranados, Lobna Ibrahim, David Latov, Cristina Wheeler-Castillo, Jacqueline Baumann, Ioline D. Henter, Carlos A. Zarate, New therapeutic targets for mood disorders. The Scientific World Journal. ,vol. 10, pp. 713- 726 ,(2010) , 10.1100/TSW.2010.65
Bengt Långström, Oleksiy Itsenko, Obaidur Rahman, [11C]Carbon monoxide, a versatile and useful precursor in labelling chemistry for PET‐ligand development Journal of Labelled Compounds and Radiopharmaceuticals. ,vol. 50, pp. 794- 810 ,(2007) , 10.1002/JLCR.1446