作者: Robert A Kyle , Clark W Heath , Paul Carbone
DOI: 10.1001/ARCHINTE.1971.00310170152022
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摘要: The occurrence of acute leukemia 1,2 and lymphoma 3 in spouses has been recognized, but that multiple myeloma not reported previously. We have had four sets whom developed their cases constitute this report. Patient Summaries 1. —A 59-year-old man complained an upper respiratory tract infection fatigue during the spring 1968 (Table 1). On a visit to his family physician November it was discovered anemia developed, he fractured rib, myeloma. patient's history unremarkable except for appendectomy 1942. findings on physical examination were within normal limits pallor. Pertinent laboratory data are presented Table 2. Serum electrophoresis revealed monoclonal protein (IgG κ) 6.5 gm/100 ml. quantitative immunoglobulin values IgG, 89; IgA, 0.22; IgM,