PERK Limits Drosophila Lifespan by Promoting Intestinal Stem Cell Proliferation in Response to ER Stress
作者： Lifen Wang , Hyung Don Ryoo , Yanyan Qi , Heinrich Jasper
DOI: 10.1371/JOURNAL.PGEN.1005220
关键词:
摘要: Intestinal homeostasis requires precise control of intestinal stem cell (ISC) proliferation. In Drosophila, this control declines with age largely due to chronic activation of stress signaling …
core.ac.uk
doaj.org参考文章(64)
Heinrich Jasper, Dirk Bohmann, Redox Regulation of Stem Cell Function Springer, Dordrecht. pp. 343- 357 ,(2013) , 10.1007/978-94-007-5787-5_12
Devanjali Dutta, Jinyi Xiang, Bruce A. Edgar, RNA Expression Profiling from FACS‐Isolated Cells of the Drosophila Intestine Current protocols in stem cell biology. ,vol. 27, ,(2013) , 10.1002/9780470151808.SC02F02S27
Bon‐Kyoung Koo, Valentina Sasselli, Hans Clevers, Retroviral Gene Expression Control in Primary Organoid Cultures Current Protocols in Stem Cell Biology. ,vol. 27, ,(2013) , 10.1002/9780470151808.SC05A06S27
Lifen Wang, Xiankun Zeng, Hyung Don Ryoo, Heinrich Jasper, Integration of UPRER and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation PLoS Genetics. ,vol. 10, pp. e1004568- ,(2014) , 10.1371/JOURNAL.PGEN.1004568
Zuzana Tothova, D. Gary Gilliland, FoxO Transcription Factors and Stem Cell Homeostasis: Insights from the Hematopoietic System Cell Stem Cell. ,vol. 1, pp. 140- 152 ,(2007) , 10.1016/J.STEM.2007.07.017
Divya Mathur, Alyssa Bost, Ian Driver, Benjamin Ohlstein, A Transient Niche Regulates the Specification of Drosophila Intestinal Stem Cells Science. ,vol. 327, pp. 210- 213 ,(2010) , 10.1126/SCIENCE.1181958
P. Walter, D. Ron, The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation Science. ,vol. 334, pp. 1081- 1086 ,(2011) , 10.1126/SCIENCE.1209038
Hyung Don Ryoo, Herman Steller, Unfolded Protein Response in Drosophila: Why Another Model Can Make It Fly Cell Cycle. ,vol. 6, pp. 830- 835 ,(2007) , 10.4161/CC.6.7.4064
Nicolas Buchon, Nichole A. Broderick, Bruno Lemaitre, Gut homeostasis in a microbial world: insights from Drosophila melanogaster. Nature Reviews Microbiology. ,vol. 11, pp. 615- 626 ,(2013) , 10.1038/NRMICRO3074
Benoît Biteau, Christine E. Hochmuth, Heinrich Jasper, JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut Cell Stem Cell. ,vol. 3, pp. 442- 455 ,(2008) , 10.1016/J.STEM.2008.07.024