INFRARED STUDIES OF NUCLEIC ACIDS

作者: M. Tsuboi

DOI: 10.1016/B978-0-408-70321-5.50011-X

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摘要: A nucleic acid in heavy water solution gives several strong absorption bands the 1700–1500 cm -1 region. The purpose of this paper is to show extent which these are useful ellucidating molecular environment each base residue question. First, some experimental aspects discussed. Secondly, on basis a normal coordinate treatment, characterization band made. Then, effects vertical stacking and inter-base hydrogen bonds Infrared spectra number DNA's, transfer RNA's, other RNA's shown with discussions pieces information obtained from them. Lastly, two examples given illustrate that infrared spectroscopy may be used for studying biologically significant interactions an aqueous system.

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