In Vitro–In Vivo Correlations in Drug Discovery and Development: Concepts and Applications in Toxicology

作者: Rex Denton , Kimberly Brannen , Bruce D. Car

DOI: 10.1002/9781118230275.CH14

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参考文章(71)
Chuenlei Parng, In vivo zebrafish assays for toxicity testing. Current Opinion in Drug Discovery & Development. ,vol. 8, pp. 100- 106 ,(2005)
Elke Genschow, Horst Spielmann, Gabriele Scholz, Ingeborg Pohl, Andrea Seiler, Nicole Clemann, Susanne Bremer, Klaus Becker, Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests. Atla-alternatives To Laboratory Animals. ,vol. 32, pp. 209- 244 ,(2004) , 10.1177/026119290403200305
Mayo M, Bringas P, Slavkin Hc, Sasano Y, Early embryonic mouse mandibular morphogenesis and cytodifferentiation in serumless, chemically defined medium: a model for studies of autocrine and/or paracrine regulatory factors. Journal of Craniofacial Genetics and Developmental Biology. ,vol. 9, pp. 185- 205 ,(1989)
Horst Spielmann, Elke Genschow, Nigel A. Brown, Aldert H. Piersma, Aart Verhoef, Marielle Q.I. Spanjersberg, Hannele Huuskonen, Francoise Paillard, Andrea Seiler, Validation of the rat limb bud micromass test in the international ECVAM validation study on three in vitro embryotoxicity tests. Atla-alternatives To Laboratory Animals. ,vol. 32, pp. 245- 274 ,(2004) , 10.1177/026119290403200306
Elke Genschow, Horst Spielmann, Andrea Seiler, Roland Buesen, Birgitta Slawik, Anke Visan, Trends in improving the embryonic stem cell test (EST): an overview. ALTEX-Alternatives to Animal Experimentation. ,vol. 21, pp. 15- 22 ,(2004)
Norbert Hinz, Ute Lessmöllmann, Diether Neubert, In vitro system for toxicological studies on the development of mammalian limb buds in a chemically defined medium. Archives of Toxicology. ,vol. 36, pp. 169- 176 ,(1976) , 10.1007/BF00351978
Rafael Moreno-Sánchez, Concepción Bravo, César Vásquez, Guadalupe Ayala, Luis H Silveira, Manuel Martı́nez-Lavı́n, Inhibition and uncoupling of oxidative phosphorylation by nonsteroidal anti-inflammatory drugs: study in mitochondria, submitochondrial particles, cells, and whole heart. Biochemical Pharmacology. ,vol. 57, pp. 743- 752 ,(1999) , 10.1016/S0006-2952(98)00330-X
J A Beavo, M Conti, R J Heaslip, Multiple cyclic nucleotide phosphodiesterases. Molecular Pharmacology. ,vol. 46, pp. 399- 405 ,(1994)
T. W. Sadler, Culture of early somite mouse embryos during organogenesis Development. ,vol. 49, pp. 17- 25 ,(1979)
E. Marshall Johnson, Regina M. Gorman, Bradley E. G. Gabel, Mindy E. George, TheHydra aftenuata system for detection of teratogenic hazards Teratogenesis, Carcinogenesis, and Mutagenesis. ,vol. 2, pp. 263- 276 ,(1982) , 10.1002/1520-6866(1990)2:3/4<263::AID-TCM1770020308>3.0.CO;2-I