Cost-effectiveness of rHu-EPO in oncology

作者: Pierre-Y. Cremieux , E. Dial , M. Gustafson , B. Sarokhan , M. B. Slavin

DOI: 10.1007/978-3-7091-7658-0_25

关键词:

摘要: Approximately 13 million Americans are diagnosed with cancer every year and the various therapies they receive often as physically trying itself [2, 26]. Pain, nausea, infection, anemia common debilitating side effects experienced by many patients undergoing chemotherapy radiotherapy. As attention has turned toward improving quality of life for treatment, advances have been made in managing these [14, 27, 33]. However, a treatment beyond traditional blood transfusions remained elusive until introduction recombinant human erythropoietin “rHu-EPO (epoetin alfa)”, which it possible to aggressively treat [10, 13, 14, 18, 22–24, 31].

参考文章(31)
José O. Bordin, Morris A. Blajchman, Immunosuppressive Effects of Allogeneic Blood Transfusions: Implications for the Patient with a Malignancy Hematology-oncology Clinics of North America. ,vol. 9, pp. 205- 218 ,(1995) , 10.1016/S0889-8588(18)30117-5
Blumberg N, Heal Jm, Effects of transfusion on immune function. Cancer recurrence and infection. Archives of Pathology & Laboratory Medicine. ,vol. 118, pp. 371- 379 ,(1994)
Peter J Neumann, Gillian D Sanders, Louise B Russell, Joanna E Siegel, Theodore G Ganiats, None, Cost-effectiveness in health and medicine Oxford University Press. ,(1996)
Jim M. Koeller, Clinical guidelines for the treatment of cancer-related anemia. Pharmacotherapy. ,vol. 18, pp. 156- 169 ,(1998) , 10.1002/J.1875-9114.1998.TB03834.X
Bert Spilker, Quality of life and pharmacoeconomics in clinical trials Lippincott-Raven. ,(1996)
J Glaspy, R Bukowski, D Steinberg, C Taylor, S Tchekmedyian, S Vadhan-Raj, Impact of therapy with epoetin alfa on clinical outcomes in patients with nonmyeloid malignancies during cancer chemotherapy in community oncology practice. Procrit Study Group. Journal of Clinical Oncology. ,vol. 15, pp. 1218- 1234 ,(1997) , 10.1200/JCO.1997.15.3.1218
L Del Mastro, M Venturini, R Lionetto, O Garrone, G Melioli, W Pasquetti, M R Sertoli, G Bertelli, G Canavese, M Costantini, R Rosso, Randomized phase III trial evaluating the role of erythropoietin in the prevention of chemotherapy-induced anemia Journal of Clinical Oncology. ,vol. 15, pp. 2715- 2721 ,(1997) , 10.1200/JCO.1997.15.7.2715
Pierre-Yves Crémieux, Barbara Barrett, Kenneth Anderson, Mitchell B. Slavin, Cost of Outpatient Blood Transfusion in Cancer Patients Journal of Clinical Oncology. ,vol. 18, pp. 2755- 2761 ,(2000) , 10.1200/JCO.2000.18.14.2755