Malignant Melanoma of the Gastrointestinal Tract: Symptoms, Diagnosis, and Current Treatment Options.
作者： Julian Teare , Julian Teare , James Larkin , Darina Kohoutova , Justin Weir
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摘要: Malignant melanoma (MM) has become the fifth most frequent cancer in UK. It is common carcinoma to metastasize gastrointestinal (GI) tract. MM particularly an affinity spread small bowel, which followed by involvement of stomach and large intestine. Excellent endoscopic options including video capsule endoscopy enteroscopy are available for a precise diagnosis GI metastatic MM. The complete surgical resection carefully selected patients not only provides symptom control, but also been associated with increase overall survival. approval BRAF-targeted therapies immune checkpoint inhibitors transformed therapeutic approaches over past decade. Currently, survival advanced who have treated combination immunotherapeutic agents reaches 52% at five years. role surgery tract evolving era effective systemic treatments.
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