Non-coding RNA therapeutics for cardiac regeneration.
作者： Luca Braga , Hashim Ali , Ilaria Secco , Mauro Giacca
DOI: 10.1093/CVR/CVAA071
关键词:
摘要: A growing body of evidence indicates that cardiac regeneration after myocardial infarction can be achieved by stimulating the endogenous capacity of cardiomyocytes (CMs) to replicate. This process is controlled, both positively and negatively, by a large set of non-coding RNAs (ncRNAs). Some of the microRNAs (miRNAs) that can stimulate CM proliferation is expressed in embryonic stem cells and is required to maintain pluripotency (eg the miR-302∼ 367 cluster). Others also govern the proliferation of different cell types …
oup.com
sci-hub.se 参考文章(201)
F. B. Engel, P. C. H. Hsieh, R. T. Lee, M. T. Keating, FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 15546- 15551 ,(2006) , 10.1073/PNAS.0607382103
Caroline L Guiner, Knut Stieger, Richard O Snyder, Fabienne Rolling, Philippe Moullier, None, Immune responses to gene product of inducible promoters. Current Gene Therapy. ,vol. 7, pp. 334- 346 ,(2007) , 10.2174/156652307782151461
Jinghai Chen, Zhan-Peng Huang, Hee Young Seok, Jian Ding, Masaharu Kataoka, Zheng Zhang, Xiaoyun Hu, Gang Wang, Zhiqiang Lin, Si Wang, Willam T. Pu, Ronglih Liao, Da-Zhi Wang, mir-17–92 Cluster Is Required for and Sufficient to Induce Cardiomyocyte Proliferation in Postnatal and Adult Hearts Circulation Research. ,vol. 112, pp. 1557- 1566 ,(2013) , 10.1161/CIRCRESAHA.112.300658
Adrien Croquelois, Andrea A. Domenighetti, Mohamed Nemir, Mario Lepore, Nathalie Rosenblatt-Velin, Freddy Radtke, Thierry Pedrazzini, Control of the adaptive response of the heart to stress via the Notch1 receptor pathway Journal of Experimental Medicine. ,vol. 205, pp. 3173- 3185 ,(2008) , 10.1084/JEM.20081427
Joacim Elmén, Morten Lindow, Sylvia Schütz, Matthew Lawrence, Andreas Petri, Susanna Obad, Marie Lindholm, Maj Hedtjärn, Henrik Frydenlund Hansen, Urs Berger, Steven Gullans, Phil Kearney, Peter Sarnow, Ellen Marie Straarup, Sakari Kauppinen, LNA-mediated microRNA silencing in non-human primates Nature. ,vol. 452, pp. 896- 899 ,(2008) , 10.1038/NATURE06783
Noriko Matsushita, Targeted MicroRNA Interference Promotes Postnatal Cardiac Cell Cycle Re-Entry. Journal of Regenerative Medicine. ,vol. 2, pp. 2- 2 ,(2013) , 10.4172/2325-9620.1000108
E. R. Porrello, A. I. Mahmoud, E. Simpson, B. A. Johnson, D. Grinsfelder, D. Canseco, P. P. Mammen, B. A. Rothermel, E. N. Olson, H. A. Sadek, Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family Proceedings of the National Academy of Sciences of the United States of America. ,vol. 110, pp. 187- 192 ,(2013) , 10.1073/PNAS.1208863110
Thomas G. Hullinger, Rusty L. Montgomery, Anita G. Seto, Brent A. Dickinson, Hillary M. Semus, Joshua M. Lynch, Christina M. Dalby, Kathryn Robinson, Christianna Stack, Paul A. Latimer, Joshua M. Hare, Eric N. Olson, Eva van Rooij, Inhibition of miR-15 Protects Against Cardiac Ischemic Injury Circulation Research. ,vol. 110, pp. 71- 81 ,(2012) , 10.1161/CIRCRESAHA.111.244442
Kazu Kikuchi, Jennifer E. Holdway, Andreas A. Werdich, Ryan M. Anderson, Yi Fang, Gregory F. Egnaczyk, Todd Evans, Calum A. MacRae, Didier Y. R. Stainier, Kenneth D. Poss, Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes Nature. ,vol. 464, pp. 601- 605 ,(2010) , 10.1038/NATURE08804
Kory J. Lavine, Slava Epelman, Keita Uchida, Kassandra J. Weber, Colin G. Nichols, Joel D. Schilling, David M. Ornitz, Gwendalyn J. Randolph, Douglas L. Mann, Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart Proceedings of the National Academy of Sciences of the United States of America. ,vol. 111, pp. 16029- 16034 ,(2014) , 10.1073/PNAS.1406508111