摘要: Over the past two decades, we have come to realize that less than 2% of our genome codes for protein-coding genes. The rest genome, much which is transcribed, small RNAs. While understanding one class RNAs, called microRNAs, has expanded greatly, new forms noncoding RNAs continue be discovered. This article reviews discovery, biogenesis and relationship between miRNAs with cancer. It also discusses classes other emerging such as eRNAs transposons.
sci-hub.se 参考文章(201)
Paul DP Pharoah, Rachel T Palmieri, Susan J Ramus, Simon A Gayther, Irene L Andrulis, Hoda Anton-Culver, Natalia Antonenkova, Antonis C Antoniou, David Goldgar, Mary S Beattie, Matthias W Beckmann, Michael J Birrer, Natalia Bogdanova, Kelly L Bolton, Wendy Brewster, Angela Brooks-Wilson, Robert Brown, Ralf Butzow, Trinidad Caldes, Maria Adelaide Caligo, Ian Campbell, Jenny Chang-Claude, Y Ann Chen, Linda S Cook, Fergus J Couch, Daniel W Cramer, Julie M Cunningham, Evelyn Despierre, Jennifer A Doherty, Thilo Doerk, Matthias Duerst, Diana M Eccles, Arif B Ekici, Douglas Easton, Peter A Fasching, Anna De Fazio, David A Fenstermacher, James M Flanagan, Brooke L Fridley, Eitan Friedman, Bo Gao, Olga Sinilnikova, Aleksandra Gentry-Maharaj, Andrew K Godwin, Ellen L Goode, Marc T Goodman, Jenny Gross, Thomas VO Hansen, Paul Harnett, Matti Rookus, Tuomas Heikkinen, Rebecca Hein, Claus Høgdall, Estrid Høgdall, Edwin S Iversen, Anna Jakubowska, Sharon E Johnatty, Beth Y Karlan, Noah D Kauff, Stanley B Kaye, Georgia Chenevix-Trench, Linda E Kelemen, Lambertus A Kiemeney, Susanne Krueger Kjaer, Diether Lambrechts, James P LaPolla, Conxi Lazaro, Nhu D Le, Arto Leminen, Karin Leunen, Douglas A Levine, Yi Lu, Lene Lundvall, Stuart Macgregor, Tamara Marees, Leon F Massuger, John R McLaughlin, Usha Menon, Marco Montagna, Kirsten B Moysich, Steven A Narod, Katherine L Nathanson, Lotte Nedergaard, Roberta B Ness, Heli Nevanlinna, Stefan Nickels, Ana Osorio, Jim Paul, Celeste Leigh Pearce, Catherine M Phelan, Malcolm C Pike, Paolo Radice, Mary Anne Rossing, Joellen M Schildkraut, Thomas A Sellers, Christian F Singer, Honglin Song, Daniel O Stram, Rebecca Sutphen, Annika Lindblom, Kathryn L Terry, Ya-Yu Tsai, Anne M Van Altena, Ignace Vergote, Robert A Vierkant, Allison F Vitonis, Christine Walsh, Shan Wang-Gohrke, Barbara Wappenschmidt, Anna H Wu, Argyrios Ziogas, Andrew Berchuck, Harvey A Risch, None, The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. Clinical Cancer Research. ,vol. 17, pp. 3742- 3750 ,(2011) , 10.1158/1078-0432.CCR-10-3405
Eulàlia Martí, Lorena Pantano, Mónica Bañez-Coronel, Franc Llorens, Elena Miñones-Moyano, Sílvia Porta, Lauro Sumoy, Isidre Ferrer, Xavier Estivill, A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing Nucleic Acids Research. ,vol. 38, pp. 7219- 7235 ,(2010) , 10.1093/NAR/GKQ575
Jan Krützfeldt, Satoru Kuwajima, Ravi Braich, Kallanthottathil G. Rajeev, John Pena, Thomas Tuschl, Muthiah Manoharan, Markus Stoffel, Specificity, duplex degradation and subcellular localization of antagomirs Nucleic Acids Research. ,vol. 35, pp. 2885- 2892 ,(2007) , 10.1093/NAR/GKM024
John L. Rinn, Howard Y. Chang, Genome Regulation by Long Noncoding RNAs Annual Review of Biochemistry. ,vol. 81, pp. 145- 166 ,(2012) , 10.1146/ANNUREV-BIOCHEM-051410-092902
Xuezhong Cai, Curt H Hagedorn, Bryan R Cullen, Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs RNA. ,vol. 10, pp. 1957- 1966 ,(2004) , 10.1261/RNA.7135204
V. Narry Kim, Jinju Han, Mikiko C. Siomi, Biogenesis of small RNAs in animals. Nature Reviews Molecular Cell Biology. ,vol. 10, pp. 126- 139 ,(2009) , 10.1038/NRM2632
Alexei Aravin, Thomas Tuschl, Identification and characterization of small RNAs involved in RNA silencing FEBS Letters. ,vol. 579, pp. 5830- 5840 ,(2005) , 10.1016/J.FEBSLET.2005.08.009
Gianpiero Di Leva, Michela Garofalo, Carlo M. Croce, MicroRNAs in cancer. Annual Review of Pathology-mechanisms of Disease. ,vol. 9, pp. 287- 314 ,(2014) , 10.1146/ANNUREV-PATHOL-012513-104715
Yuping Mei, David Clark, Li Mao, Novel dimensions of piRNAs in cancer Cancer Letters. ,vol. 336, pp. 46- 52 ,(2013) , 10.1016/J.CANLET.2013.04.008
Junichi Takamizawa, Hiroyuki Konishi, Kiyoshi Yanagisawa, Shuta Tomida, Hirotaka Osada, Hideki Endoh, Tomoko Harano, Yasushi Yatabe, Masato Nagino, Yuji Nimura, Tetsuya Mitsudomi, Takashi Takahashi, Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival Cancer Research. ,vol. 64, pp. 3753- 3756 ,(2004) , 10.1158/0008-5472.CAN-04-0637