The papillomavirus virion: a machine built to hide molecular Achilles' heels.
作者： Christopher B. Buck , Benes L. Trus
DOI: 10.1007/978-1-4614-0980-9_18
关键词:
摘要: Papillomaviruses are a diverse group of DNA viruses that infect the skin and mucosal tissues vertebrates. More than 100 distinct human papillomavirus (HPV) genotypes have so far been identified. A subset HPVs is known to cause cancer. Although recently developed vaccines protect vaccinated individuals from two most carcinogenic HPV types, there pressing need for next-generation might offer broad-spectrum protection against full range cancer-causing HPVs. The ongoing development such will be facilitated by deeper understanding mechanics assembly nonenveloped virion, as well machinelike structural changes occur in virion during process infectious entry into host cells. This chapter reviews field’s current knowledge these aspects biology speculates about areas where further work needed.
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Ulf Lindahl, Jeffrey D. Esko, Koji Kimata, John Couchman, Proteoglycans and Sulfated Glycosaminoglycans Edition:3rd. ,(2009) , 10.1101/GLYCOBIOLOGY.3E.017
Douglas R. Lowy, History of Papillomavirus Research The Papillomaviruses. pp. 13- 28 ,(2007) , 10.1007/978-0-387-36523-7_2
Christopher B. Buck, Diana V. Pastrana, Douglas R. Lowy, John T. Schiller, Generation of HPV pseudovirions using transfection and their use in neutralization assays. Methods in molecular medicine. ,vol. 119, pp. 445- 462 ,(2005) , 10.1385/1-59259-982-6:445
E. Schwarz, M. Dürst, C. Demankowski, O. Lattermann, R. Zech, E. Wolfsperger, S. Suhai, H. zur Hausen, DNA sequence and genome organization of genital human papillomavirus type 6b. The EMBO Journal. ,vol. 2, pp. 2341- 2348 ,(1983) , 10.1002/J.1460-2075.1983.TB01744.X
G. A. Bagiyan, I. K. Koroleva, N. V. Soroka, A. V. Ufimtsev, Oxidation of thiol compounds by molecular oxygen in aqueous solutions Russian Chemical Bulletin. ,vol. 52, pp. 1135- 1141 ,(2003) , 10.1023/A:1024761324710
Schwartz S, Regulation of human papillomavirus late gene expression. Upsala Journal of Medical Sciences. ,vol. 105, pp. 171- ,(2000)
Alison A. McBride, Replication and partitioning of papillomavirus genomes. Advances in Virus Research. ,vol. 72, pp. 155- 205 ,(2008) , 10.1016/S0065-3527(08)00404-1
J.T. Finch, A. Klug, The structure of viruses of the papilloma-polyoma type 3. Structure of rabbit papilloma virus, with an appendix on the topography of contrast in negative-staining for electron-microscopy. Journal of Molecular Biology. ,vol. 13, pp. 1- 12 ,(1965) , 10.1016/S0022-2836(65)80075-4
Walter Manger, Shishir Gadam, Shilu Wu, Qinjian Zhao, Novel process for making human papillomavirus virus-like particles with improved properties ,(2000)
Martin Sapp, Claudia Fligge, Ingrid Petzak, J. Robin Harris, Rolf E. Streeck, Papillomavirus Assembly Requires Trimerization of the Major Capsid Protein by Disulfides between Two Highly Conserved Cysteines Journal of Virology. ,vol. 72, pp. 6186- 6189 ,(1998) , 10.1128/JVI.72.7.6186-6189.1998