Malignant myoepithelioma arising from recurrent pleomorphic adenoma of the soft palate.

摘要: Malignant myoepithelioma is a rare salivary gland neoplasm that can arise either de novo or within pre-existing pleomorphic adenoma. We report case of malignant arising from adenoma the soft palate. A 70-year-old woman presented in our department with very large tumor The patient had history at same location was surgically removed 2 years ago. second operation, intraoral excision performed. Histological examination recurrence revealed spindle cell an infiltrative growth pattern and high mitotic rate. Immunohistochemical investigation confirmed diagnosis low-grade carcinoma myoepithelial origin free surgical margins. remains disease for more than twelve months after end treatment.