CAR T-cell therapy for pancreatic cancer.
作者： Carl J. DeSelm , Zachary E. Tano , Anna M. Varghese , Prasad S. Adusumilli
DOI: 10.1002/JSO.24627
关键词:
摘要: … on various cancer cell surface antigens—MSLN, CEA, MUC1, … In this test, administration of 500 000 CAR T cells led to 100… with untransduced T cells,76 thereby establishing MUC1 as a …
sci-hub.se 参考文章(143)
G. H. Robert Albers, Gertjan Fleuren, Maria J. Escribano, Marius Nap, Immunohistochemistry of CEA in the human pancreas during development, in the adult, chronic pancreatitis, and pancreatic adenocarcinoma. American Journal of Clinical Pathology. ,vol. 90, pp. 17- 22 ,(1988) , 10.1093/AJCP/90.1.17
Laura Soucek, Joseph J. Buggy, Roderik Kortlever, Shanthi Adimoolam, Helena Allende Monclús, Maria Teresa Salcedo Allende, Lamorna Brown Swigart, Gerard I. Evan, Modeling Pharmacological Inhibition of Mast Cell Degranulation as a Therapy for Insulinoma Neoplasia. ,vol. 13, pp. 1093- 1100 ,(2011) , 10.1593/NEO.11980
Kentaro Minagawa, Xiaoou Zhou, Shin Mineishi, Antonio Di Stasi, Seatbelts in CAR therapy: How Safe Are CARS? Pharmaceuticals. ,vol. 8, pp. 230- 249 ,(2015) , 10.3390/PH8020230
Shintaro Takeuchi, Muhammad Baghdadi, Takahiro Tsuchikawa, Haruka Wada, Toru Nakamura, Hirotake Abe, Sayaka Nakanishi, Yuu Usui, Kohtaro Higuchi, Mizuna Takahashi, Kazuho Inoko, Syoki Sato, Hironobu Takano, Toshiaki Shichinohe, Ken-ichiro Seino, Satoshi Hirano, Chemotherapy-derived inflammatory responses accelerate the formation of immunosuppressive myeloid cells in the tissue microenvironment of human pancreatic cancer Cancer Research. ,vol. 75, pp. 2629- 2640 ,(2015) , 10.1158/0008-5472.CAN-14-2921
C.-Y. Wu, K. T. Roybal, E. M. Puchner, J. Onuffer, W. A. Lim, Remote control of therapeutic T cells through a small molecule-gated chimeric receptor Science. ,vol. 350, pp. 4077- ,(2015) , 10.1126/SCIENCE.AAB4077
Eun-Kee Park, Alessandra Sandrini, Deborah H. Yates, Jenette Creaney, Bruce W. Robinson, Paul S. Thomas, Anthony R. Johnson, Soluble mesothelin-related protein in an asbestos-exposed population: the dust diseases board cohort study. American Journal of Respiratory and Critical Care Medicine. ,vol. 178, pp. 832- 837 ,(2008) , 10.1164/RCCM.200802-258OC
Ingunn M. Stromnes, Thomas M. Schmitt, Ayaka Hulbert, J. Scott Brockenbrough, Hieu N. Nguyen, Carlos Cuevas, Ashley M. Dotson, Xiaoxia Tan, Jennifer L. Hotes, Philip D. Greenberg, Sunil R. Hingorani, T Cells Engineered against a Native Antigen Can Surmount Immunologic and Physical Barriers to Treat Pancreatic Ductal Adenocarcinoma Cancer Cell. ,vol. 28, pp. 638- 652 ,(2015) , 10.1016/J.CCELL.2015.09.022
Sjoukje J. C. van der Stegen, David M. Davies, Scott Wilkie, Julie Foster, Jane K. Sosabowski, Jerome Burnet, Lynsey M. Whilding, Roseanna M. Petrovic, Sadaf Ghaem-Maghami, Stephen Mather, Jean-Pierre Jeannon, Ana C. Parente-Pereira, John Maher, Preclinical In Vivo Modeling of Cytokine Release Syndrome Induced by ErbB-Retargeted Human T Cells: Identifying a Window of Therapeutic Opportunity? Journal of Immunology. ,vol. 191, pp. 4589- 4598 ,(2013) , 10.4049/JIMMUNOL.1301523
Aurore Morello, Michel Sadelain, Prasad S. Adusumilli, Mesothelin-Targeted CARs: Driving T Cells to Solid Tumors Cancer Discovery. ,vol. 6, pp. 133- 146 ,(2016) , 10.1158/2159-8290.CD-15-0583
Albert Lo, Liang-Chuan S. Wang, John Scholler, James Monslow, Diana Avery, Kheng Newick, Shaun O'Brien, Rebecca A. Evans, David J. Bajor, Cynthia Clendenin, Amy C. Durham, Elizabeth L. Buza, Robert H. Vonderheide, Carl H. June, Steven M. Albelda, Ellen Puré, Tumor-promoting desmoplasia is disrupted by depleting FAP-expressing stromal cells Cancer Research. ,vol. 75, pp. 2800- 2810 ,(2015) , 10.1158/0008-5472.CAN-14-3041