Cadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubule cells
作者： Wing-Kee Lee , Blazej Torchalski , Frank Thévenod
DOI: 10.1152/AJPCELL.00197.2007
关键词:
摘要: A major target of cadmium (Cd2+) toxicity is the kidney proximal tubule (PT) cell. Cd2+-induced apoptosis PT cells mediated by sequential activation calpains at 3–6 h and caspases-9 -3...
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