The Pneumococcal Polysaccharides: A Re-Examination

摘要: Publisher Summary The pneumococcal polysaccharides and their antisera are used in the immunological characterization of other polysaccharides. Structural studies these special importance, this chapter summarizes results such studies. Studies a great number extracellular from Gram-positive Gram-negative bacteria indicate that they composed oligosaccharide repeating-units. synthesis bacterial polysaccharide requires considerable highly specific enzymes, increasing with complexity repeating unit. purification may be difficult, material is sometimes contaminated by cell-wall component known as “C-substance.” methods for structural analysis not always adequate, especially when quantitative significance needed. Sometimes, it even difficult to obtain satisfactory, sugars. Furthermore, considering importance compounds immunochemistry further work field