Ocular side effects of selected systemic drugs.

摘要: Numerous systemic drugs produce adverse effects that involve the eye. Pigmentary inclusions of lids or conjunctivae both may be caused by a variety drugs, including amiodarone, chlorpromazine, and gold salts, while conjunctivitis blepharoconjunctivitis have been associated with isotretinoin, sulfonamides, salicylates, antineoplastic agents. Dry eye complaints antihistamines, beta-receptor blocking agents prescribed for cardiovascular problems, antianxiety agents, tricyclic antidepressants. Several well documented as causes keratopathies and/or lenticular deposits, chloroquine hydroxychloroquine, corticosteroids, nonsteroidal antiinflammatory antiarrhythmic agent amiodarone. Visual acuity decreased transient changes in refractive error antifungal metronidazole, thiazide diuretics, carbonic anhydrase inhibitors. Dilation pupil anticholinergic antidepressant central nervous system stimulants such cocaine, methylphenidate, amphetamines. Nystagmus, diplopia, extraocular muscle palsies depressants, barbiturates, elevated blood ethanol concentrations. Intraocular pressure can susceptible individuals long-term use topical corticosteroids. retinal toxicity, thioridazine, tamoxifen, talc, which embolize to circulation when administered drug abusers. The antituberculosis ethambutol isoniazid implicated reduced acuity, visual field defects, disturbances color vision. Optic neuritis retrobulbar result from chloramphenicol. This paper describes these other ocular encountered examining patients who are taking drugs.