The modified-Mannich reaction: Conversion of arylboronic acids and subsequent coupling with paraformaldehyde and amines toward the one-pot synthesis of Mannich bases and benzoxazines
作者： Juan Liu , Gaoqing Yuan
DOI: 10.1016/J.TETLET.2017.02.081
关键词:
摘要: Abstract A modified Mannich reaction has been developed for the synthesis of bases and benzoxazines via oxidative hydroxylation arylboronic acids subsequent coupling with paraformaldehyde amines in one pot. This is easily carried out to afford target products good excellent yields tolerates a variety functional groups.
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