Muskelinvasives Harnblasenkarzinom nach radikaler Zystektomie

作者: A.K. Thissen , D. Pfister , A. Heidenreich

DOI: 10.1007/S00120-013-3311-5

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摘要: Hintergrund Die Indikation zur Einleitung einer adjuvanten Chemotherapie beim Urothelkarzinom der Harnblase nach radikaler Zystektomie wird entsprechend verschiedenen internationalen Leitlinien aufgrund suboptimalen Evidenz zunehmend kritisch beurteilt. Die adjuvante Therapie sollte ungunstigen Evidenzsituation vornehmlich klinischen Studien vorbehalten werden. Unter Bedingungen konnte die bei Patienten mit ausgedehnten lymphknotenpositiven Befunden eingesetzt Klinische, pathohistologische und molekulare Risikofaktoren, einem gunstigen bzw. Ansprechen auf verbunden sind, werden in Literatur nur sparlich beschrieben.

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