Increased intracortical inhibition in hyperglycemic hemichorea-hemiballism.
作者： Jie‐Yuan Li , Robert Chen , None
DOI: 10.1002/MDS.25940
关键词:
摘要: Hemichorea-hemiballism (HC-HB) in uncontrolled diabetes mellitus is an uncommon manifestation of hyperglycemia. The pathophysiology hyperglycemic HC-HB not well understood. A previous report showed increased intracortical inhibition the motor cortex a patient with HC-HB. objective this study to investigate excitability patients We hypothesized that measured transcranial magnetic stimulation, which likely reflects cortical γ-aminobutyric acid (GABA)ergic circuits, would be impaired studied 15 mean age 71.5 years (range, 48-94 y) and 12 age-matched healthy subjects. contralateral hemichorea was tested. Transcranial stimulation measures included evoked potential, recruitment curve, GABAA mediated short interval inhibition, facilitation, GABAB silent period duration long inhibition. No significant difference found threshold, curve response, or facilitation both rest active conditions between normal However, significantly during muscle activation but at also concluded are HC-HB, only activation. may associated receptor-mediated inhibitory activity cortex. © 2014 International Parkinson Movement Disorder Society
sci-hub.se 参考文章(48)
Seung-Hun Oh, Kyung-Yul Lee, Joo-Hyuk Im, Myung-Sik Lee, Chorea associated with non-ketotic hyperglycemia and hyperintensity basal ganglia lesion on T1-weighted brain MRI study: a meta-analysis of 53 cases including four present cases. Journal of the Neurological Sciences. ,vol. 200, pp. 57- 62 ,(2002) , 10.1016/S0022-510X(02)00133-8
M Inghilleri, A Berardelli, G Cruccu, M Manfredi, Silent period evoked by transcranial stimulation of the human cortex and cervicomedullary junction. The Journal of Physiology. ,vol. 466, pp. 521- 534 ,(1993) , 10.1113/JPHYSIOL.1993.SP019732
Robert Chen, Didier Cros, Antonio Curra, Vincenzo Di Lazzaro, Jean-Pascal Lefaucheur, Michel R. Magistris, Kerry Mills, Kai M. Rösler, William J. Triggs, Yoshikazu Ugawa, Ulf Ziemann, The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committee. Clinical Neurophysiology. ,vol. 119, pp. 504- 532 ,(2008) , 10.1016/J.CLINPH.2007.10.014
F. Tergau, Veronika Wanschura, Monica Canelo, Stephan Wischer, Eric M. Wassermann, U. Ziemann, Walter Paulus, Complete suppression of voluntary motor drive during the silent period after transcranial magnetic stimulation. Experimental Brain Research. ,vol. 124, pp. 447- 454 ,(1999) , 10.1007/S002210050640
T Kujirai, M D Caramia, J C Rothwell, B L Day, P D Thompson, A Ferbert, S Wroe, P Asselman, C D Marsden, Corticocortical inhibition in human motor cortex. The Journal of Physiology. ,vol. 471, pp. 501- 519 ,(1993) , 10.1113/JPHYSIOL.1993.SP019912
Ronald B Posturna, Anthony E Lang, Hemiballism: revisiting a classic disorder Lancet Neurology. ,vol. 2, pp. 661- 668 ,(2003) , 10.1016/S1474-4422(03)00554-4
Kon Chu, Dong-Wha Kang, Dong-Eog Kim, Seong-Ho Park, Jae-Kyu Roh, Diffusion-Weighted and Gradient Echo Magnetic Resonance Findings of Hemichorea-Hemiballismus Associated With Diabetic Hyperglycemia Archives of Neurology. ,vol. 59, pp. 448- 452 ,(2002) , 10.1001/ARCHNEUR.59.3.448
Terence D. Sanger, Rami R. Garg, Robert Chen, Interactions between two different inhibitory systems in the human motor cortex. The Journal of Physiology. ,vol. 530, pp. 307- 317 ,(2001) , 10.1111/J.1469-7793.2001.0307L.X
Alexxai V Kravitz, Benjamin S Freeze, Philip RL Parker, Kenneth Kay, Myo T Thwin, Karl Deisseroth, Anatol C Kreitzer, None, Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry Nature. ,vol. 466, pp. 622- 626 ,(2010) , 10.1038/NATURE09159
R. Cantello, M. Gianelli, D. Bettucci, C. Civardi, M. S. De Angelis, R. Mutani, Parkinson's disease rigidity: Magnetic motor evoked potentials in a small hand muscle Neurology. ,vol. 41, pp. 1449- 1449 ,(1991) , 10.1212/WNL.41.9.1449