Potential applications of the quantitative susceptibility mapping (QSM) in MR-guided radiation therapy.

摘要: Magnetic resonance-guided radiation therapy (MR-GRT) offers great potential to improve treatment outcomes by providing more accurate and patient-tailored therapy. Despite superior soft tissue contrast in MRI, one of the challenges towards MRI-only workflows is that process often requires some sort 'MR-invisible' metal-based devices. In this study, feasibility quantitative susceptibility mapping (QSM) for visualization MR-invisible devices was studied. Our recently proposed QSM-based algorithm brachytherapy seed modified optimized different including: seeds, plastic interstitial needles, CT-markers obturators, types fiducial markers agar, prostate meat phantoms were All scanned using 3T MR scanner with a 3D multi-echo gradient recalled echo (ME-GRE) pulse sequence. The QSM results all compared CT images spatial accuracy QSM. applied post-processing found be insensitive seeds' type; also, presence nearby calcifications had no effect on visualization. successfully generated positive both investigated high CT. Interstitial needles containing aluminum-based CT-maker titanium-based obturators accurately depicted technique relies standard sequences visualize conventional metallic CT-like solely through post-processing. Upon vivo validation technique, may have replace an MR-only guided