Synthesis of α-trifluoromethyl unsaturated acids and derivatives

作者: Frédérique Tellier , Max Audouin , Raymond Sauvêtre

DOI: 10.1016/S0022-1139(01)00542-5

关键词:

摘要: A one pot synthesis of α-trifluoromethyl unsaturated acids via a [3,3]-sigmatropic rearrangement allyl (or propargyl) fluorovinyl ethers is described. By proto- and iodolactonization, these lead to the corresponding trifluoromethylated lactones.

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