Lipophilic-polycationic delivery systems

作者: Maria Tomoaia-Cotisel , Robert Katz

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摘要: The present invention describes site-specific biomolecular complexes comprising a therapeutic, prophylactic and diagnostic agent, called also biologically active molecule an omega-3 fatty acid derivatives thereof. are further covalently bonded with cationic carriers permeabilizer peptides for delivery across the blood-brain barrier targeting moieties uptake by target brain cells. Said particularly useful of agent to glial tissue as well cortical, cholinergic adrenergic neurons. preferred therapeutic or conjugates comprise such alpha-linolenic acid, eicosapentaenoic docosahexaenoic

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