Delirium predicts 12-month mortality.

摘要: Background Delirium has not been found to be a significant predictor of postdischarge mortality, but previous research methodologic limitations including small sample sizes and inadequate control confounding. This study aimed determine the independent effects presence delirium, type delirium (incident vs prevalent), severity symptoms on 12-month mortality among older medical inpatients. Methods A prospective, observational 2 cohorts inpatients was conducted with patients 65 years or older: 243 had prevalent incident 118 controls no delirium. Baseline measures included and/or dementia, symptoms, physical function, comorbidity, physiological clinical illness. Mortality during 12 months after enrollment analyzed Cox proportional hazards model adjustment for covariates. Results The unadjusted hazard ratio 3.44 (95% confidence interval, 2.05-5.75); adjusted 2.11 1.18-3.77). effect sustained over entire period covariates stronger without dementia. Among there weak, nonsignificant survival. After covariates, did differ between greater associated higher mortality. Conclusions is an marker increased hospital admission. It particularly important prognostic