Bacterial contamination of dialysate in dialysis-associated endotoxaemia.

摘要: Abstract Bacteriological investigations and endotoxin (ET) determinations were performed during a routine haemodialysis session for six patients. The glucose free dialysate was prepared with untreated tap water. All patients dialysed 5 h. Pseudomonas aeruginosa regularly isolated in numbers up to 10 7 cfu ml −1 from samples of the inflow, site outflow. ET levels plasma increased continuously always higher blood outflow line dialyzer than inflow. Despite high bacterial counts increasing neither bacteraemia nor fever observed. former is due impermeability membrane bacteria, latter explained by low pyrogenicity P. endotoxin. Inspection machines revealed that air-traps heater-unit incoming (untreated) water before mixing concentrate only sites where release feasible, as this part machine escaped disinfection construction these devices. We recommend regular all parts machine, including heating units, air traps valves.