Cognitive Aging : Role of Cardiovascular Disease Risk Factors

摘要: Several cardiovascular disease risk factors including, dyslipidemia, high blood pressure, and diabetes have been proposed as important modifiable for cognitive decline dementia. These often co-occur their aggregation is associated with increased of However, studies composite measures in relation to outcomes non-elderly populations are scarce. The aim this thesis was examine cognition longitudinal change amongmiddle-aged adults. Data from the Whitehall II study were used associations between metabolic syndrome, two Framingham scores; stroke general scores, cognition, based on three assessments over 10 years. In addition, these (cardio)vascular scores compared CAIDE dementia score. Of all examined, best predictors 10-year decline. Higher faster inmultiple tests including verbal fluency, vocabulary global cognition. results suggest that multiple contribute starting midlife multi-risk factor models such may be better suited assessing Early identification treatment offer possibility markedly delaying or preventing