Lactate level, etiology, and mortality of adult patients in an emergency department: a cohort study

摘要: Background Increased lactate is associated with high mortality among patients suspected infection or trauma in the emergency department (ED), but association other aetiologies less well described. The aim of this study was to describe relation between lactate, aetiology and 7-day adult ED patients. Methods A retrospective cohort all who had a measured within 4 h after arrival at Odense University Hospital June 2012 May 2013. categorisation based on discharge diagnoses. Results 5360 were included; 51.7% men, median age 67 years (IQR 50–79). 77.2% low (0–1.9 mmol/L), 16.2% intermediate (2–3.9 6.6% (≥4 mmol/L). 2.9% (95% CI 2.4% 3.5%) for 7.8% 6.1% 9.8%) 23.9% 19.6% 28.8%) lactate. level varied across different diagnostic groups. Based Area Under Curve receiver operating characteristic analysis, showed be useful (0.78, 95% 0.73 0.84), 0.65 0.92), cardiac diseases (0.83, 0.75 0.91) gastrointestinal 0.68 0.98). Lactate not neurological (0.58, 0.50 0.67) respiratory disease (0.64, 0.55 0.74), uncertain value remaining Conclusions Among patients, prognostic varies