Pre- and Postsynaptic Effects of Glutamate in the Frog Labyrinth.
作者： Maria Lisa Rossi , Gemma Rubbini , Marta Martini , Rita Canella , Riccardo Fesce
DOI: 10.1016/J.NEUROSCIENCE.2018.06.016
关键词:
摘要: Abstract The role of glutamate in quantal release at the cytoneural junction was examined by measuring mEPSPs and afferent spikes posterior canal intact frog labyrinth. Release enhanced exogenous glutamate, or dl -TBOA, a blocker reuptake. Conversely, drugs acting on ionotropic receptors did not affect release; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) CNQX decreased mEPSP size dose-dependent manner; NMDA-R d -AP5 concentrations
sci-hub.se 参考文章(51)
Shin-ichi Usami, Yutaka Takumi, Atsushi Matsubara, Shigetoshi Fujita, Ole P. Ottersen, Neurotransmission in the vestibular endorgans--glutamatergic transmission in the afferent synapses of hair cells. Biological Sciences in Space. ,vol. 15, pp. 367- 370 ,(2001) , 10.2187/BSS.15.367
Jérémie Bonsacquet, Aurore Brugeaud, Vincent Compan, Gilles Desmadryl, Christian Chabbert, AMPA type glutamate receptor mediates neurotransmission at turtle vestibular calyx synapse. The Journal of Physiology. ,vol. 576, pp. 63- 71 ,(2006) , 10.1113/JPHYSIOL.2006.116467
Nobuhiro Hakuba, Kenichiro Koga, Kiyofumi Gyo, Shin-ichi Usami, Kohichi Tanaka, Exacerbation of Noise-Induced Hearing Loss in Mice Lacking the Glutamate Transporter GLAST The Journal of Neuroscience. ,vol. 20, pp. 8750- 8753 ,(2000) , 10.1523/JNEUROSCI.20-23-08750.2000
Marta Martini, Rita Canella, Gemma Rubbini, Riccardo Fesce, Maria Lisa Rossi, Sensory transduction at the frog semicircular canal: how hair cell membrane potential controls junctional transmission. Frontiers in Cellular Neuroscience. ,vol. 9, pp. 235- 235 ,(2015) , 10.3389/FNCEL.2015.00235
JM Annoni, SL Cochran, W Precht, Pharmacology of the vestibular hair cell-afferent fiber synapse in the frog. The Journal of Neuroscience. ,vol. 4, pp. 2106- 2116 ,(1984) , 10.1523/JNEUROSCI.04-08-02106.1984
Saaid Safieddine, Robert J. Wenthold, The Glutamate Receptor Subunit δ1 Is Highly Expressed in Hair Cells of the Auditory and Vestibular Systems The Journal of Neuroscience. ,vol. 17, pp. 7523- 7531 ,(1997) , 10.1523/JNEUROSCI.17-19-07523.1997
Y. Zilberstein, M. C. Liberman, G. Corfas, Inner Hair Cells Are Not Required for Survival of Spiral Ganglion Neurons in the Adult Cochlea The Journal of Neuroscience. ,vol. 32, pp. 405- 410 ,(2012) , 10.1523/JNEUROSCI.4678-11.2012
J. Ruel, C. Chen, R. Pujol, R. P. Bobbin, J. L. Puel, AMPA-preferring glutamate receptors in cochlear physiology of adult guinea-pig The Journal of Physiology. ,vol. 518, pp. 667- 680 ,(1999) , 10.1111/J.1469-7793.1999.0667P.X
P.S Guth, P Perin, C.H Norris, P Valli, The vestibular hair cells:post-transductional signal processing Progress in Neurobiology. ,vol. 54, pp. 193- 247 ,(1998) , 10.1016/S0301-0082(97)00068-3
S. G. Sadeghi, S. J. Pyott, Z. Yu, E. Glowatzki, Glutamatergic signaling at the vestibular hair cell calyx synapse. The Journal of Neuroscience. ,vol. 34, pp. 14536- 14550 ,(2014) , 10.1523/JNEUROSCI.0369-13.2014