Guarana (Paullinia cupana) presents a safe and effective anti-fatigue profile in patients with chronic kidney disease: A randomized, double-blind, three-arm, controlled clinical trial
作者： Ieda Maria Pedroso Dorneles , Mateus Batista Fucks , Paula Caitano Fontela , Matias Nunes Frizzo , Eliane Roseli Winkelmann
DOI: 10.1016/J.JFF.2018.10.004
关键词:
摘要: Abstract The effects of guarana (Paullinia cupana) supplementation in capsules, for 30 days, were evaluated the following dosages: placebo, 200 mg/day, and 400 mg/day. Clinical symptomatology, hematological, biochemical, renal function parameters chronic kidney disease patients undergoing hemodialytic treatment. Most groups 200 mg/day 400 mg/day reported increased mood/energy, decreased fatigue, appetite. rate reporting headache, insomnia, gastric discomfort, nausea/vomiting was higher group, while most placebo group did not report any changes. had hemoglobin hematocrit values after 30 days when compared to group. Additionally, a reduction hematological increase glucose seen Guarana, especially at dosage is safe effective improving clinical symptoms maintaining values.
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