A new player in bacterial sulfide-inducible transcriptional regulation.

摘要: Summary Although hydrogen sulfide (H2S) is perhaps best known as a toxic gas, the electron-rich H2S functions an energy source and electron donor for chemolithotrophic photosynthetic bacteria, via oxidation, universal substrate cysteine biosynthesis. These distinct harmful beneficial roles of suggest need to “sense” prevailing concentrations downstream reactive sulfur species (RSS) regulate expression genes mediating homeostasis. The paper by Li et al. in this issue Molecular Microbiology adds Cupriavidus FisR expanding repertoire regulatory mechanisms that bacteria have evolved sense cellular RSS mitigate their deleterious effects. This article protected copyright. All rights reserved.