作者: T Westers , A Jones-Bitton , P Menzies , J VanLeeuwen , Z Poljak
DOI: 10.1016/J.PREVETMED.2016.09.021
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摘要: Haemonchosis is often associated with late gestation and parturition in ewes Canada. Due to widespread concerns about development of anthelmintic resistance (AR), targeted selective treatment (TST), where individual animals are treated an rather than the entire flock, a possible strategy control clinical signs recently lambed while still maintaining parasite refugia. Performing fecal egg counts (FEC) on cost-prohibitive, so indicators that identify high FEC essential for TST programs. The study objectives were to: a) evaluate ability four periparturient Haemonchus sp. b) determine appropriate thresholds statistically-significant indicators. A field was conducted during 2013 2014 lambing seasons (February-May) three client-owned farms Ontario documented AR problems haemonchosis ewes. Ewes examined within days selected oral closantel (10mg/kg body weight), novel Canada, if they met at least one criteria: last grazing season their first season; condition score ≤2; c) Faffa Malan Chart (FAMACHA©) ≥3; and/or d) or more nursing lambs. Fecal samples collected per rectum day from each 20 randomly untreated farm. percentages farm, as determined by coproculture, ranged 53% 92% total trichostrongyle-type counts. Mean FECs significantly higher (n=136) (n=103) both years (p=0.001), suggesting suitable identifying FEC. linear mixed model fit logarithmic-transformed outcome variable, year fixed effects, farm random effect. FAMACHA© sole indicator remain (p=0.002). receiver-operator curve test sensitivity maximized (92.4%) ≥3 indicator. should therefore be included programs requiring due