A new radionuclide approach for the quantification of left ventricular volumes: the 'geometric count based' method.

摘要: A new radionuclide method, called the 'geometric count based' (GCB) has been developed for quantification of absolute left ventricular volume. As method is based on planar ventriculography, it non-invasive and simple, avoids relatively cumbersome longer lasting, dynamic procedure using single photon computed emission tomography, which can be used achieving same goal. The purpose this study was to describe exactness theoretical approach validate its accuracy both by physical experiments initial clinical trial, as compared contrast ventriculography. Count data were combined with geometric assuming an ellipsoid shape identical short axes. following equation computing end diastolic volume, EDV (in ml) developed: EDV=2cMCtot/Cmax, where c manually drawn axis (one row pixel ROI) prolate in LAO 45 degrees (cm), M calibrated size cm2), Ctot total counts LV ROI, Cmax maximum ROI. Physical two different 'heart shaped' phantoms compare results obtained GCB true phantom volumes ball (BLV), other authors. cylindrical 112.5 ml 190.5 114 196 168 180 BLV methods, respectively. In a study, measured plane ventriculography 38 coronary patients. good correlation between systolic (r=0.94, r=0.90). Both studies indicate that accurate, simple measuring volumes. Additionally, could even smallest nuclear medicine units, example intensive care units there are mobile cameras.