Method of identifying compounds that bind to the insect gaba receptor

作者: Michael D. Tomalski , Daniel B. Gant

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摘要: The present invention provides a method of measuring the ability compound to bind GABA recognition site an insect receptor. further host cells that express nucleic acid encoding receptor subunit LCCH3 and Grd, cell membranes obtained from cells.

参考文章(3)
R. H. Ffrench-Constant, Hwa-Jung Lee, M. B. Jackson, T. Rocheleau, Hai-Guang Zhang, SUBUNIT COMPOSITION DETERMINES PICROTOXIN AND BICUCULLINE SENSITIVITY OF DROSOPHILA GAMMA -AMINOBUTYRIC ACID RECEPTORS Molecular Pharmacology. ,vol. 48, pp. 835- 840 ,(1995)