The impact of previous ureteroscopic tumor ablation on oncologic outcomes after radical nephrouretectomy for upper urinary tract urothelial carcinoma

作者: Cenk Gurbuz , Ramy F. Youssef , Shahrokh F. Shariat , Yair Lotan , Christopher G. Wood

DOI: 10.1089/END.2010.0396

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摘要: Abstract We investigated whether a history of endoscopic tumor ablation impacts oncologic outcomes after radical nephroureterectomy (RNU) for upper urinary tract urothelial carcinoma (UTUC). Using multi-institutional database that contained patients who were treated with RNU, assessed according to ureteroscopic ablation. Disease-free survival (DFS) and cancer-specific (CSS) estimated using the Kaplan-Meier analysis. Multivariate Cox regression analyses performed determine independent predictors disease recurrence mortality RNU. The study included 1268 patients, 853 men 415 women, mean age 67.5 years (range 32–94 y) 52.8 months median follow-up A total 175 (13%) underwent RNU 1093 (87%) without 5-year DFS CSS rates 72% 77% in those a...

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