Monitored anaesthesia care in the elderly: guidelines and recommendations.

作者: Margaret Ekstein , Doron Gavish , Tiberiu Ezri , Avi A Weinbroum

DOI: 10.2165/00002512-200825060-00003

关键词:

摘要: As the number of elderly patients undergoing surgery continues to rise, it is important consider anaesthetic options that minimize physiological stress in these patients. Monitored anaesthesia care (MAC), or sedation and monitoring during surgery, an attractive option for certain common procedures. However, those administering MAC must normal decline functional reserve aged >70 years. This includes loss compensation hypovolaemia, decreased peripheral vascular resistance, altered mental status reduced response hypoxia hypercarbia associated with perioperative sedated state this population. In addition, vigilance necessary identify co-morbid states, which increase incidence age often present atypically. Elderly have increased sensitivity all sedatives opioids (doubled by 80 years, quadrupled 90 years benzodiazepines). a result changes body composition, as well senescence renal hepatic function, time onset offset even short-acting will be prolonged. There also extreme variability among Anaesthetic dosing should smaller increments elderly, boluses half infusions much two-thirds. Caution exercised through full intra-operative postoperative status, oxygenation perfusion states. Pain best treated using doses multimodal regimen, aim being reduce adverse effects while ensuring adequate pain relief. way, huge range procedures can safely performed our aging population expectations early return baseline status.

参考文章(138)
Michael Weissel, Disturbances of thyroid function in the elderly Wiener klinische Wochenschrift. ,vol. 118, pp. 16- 20 ,(2006) , 10.1007/S00508-005-0504-Y
O'Connor M, Cooper Gm, Mark J, Harvey J, Effect of alfentanil and fentanyl on recovery from brief anaesthesia. BJA: British Journal of Anaesthesia. ,vol. 55, ,(1983)
Ben-Abraham R, Weinbroum Aa, Ogorek D, Dexmedetomidine: a promising agent for anesthesia and perioperative care. Israel Medical Association Journal. ,vol. 2, pp. 793- ,(2000)
A Crawford-Sykes, M Scarlett, M Nelson, Preoperative starvation and pulmonary aspiration. New perspectives and guidelines. West Indian Medical Journal. ,vol. 51, pp. 241- 245 ,(2002)
Jorge G. Ruiz, David T. Lowenthal, NSAIDS and nephrotoxicity in the elderly Geriatric Nephrology and Urology. ,vol. 7, pp. 51- 57 ,(1997) , 10.1023/A:1008288532636
S. Eisig, M. Cohen, R. A. Kraut, Comparison of recovery of propofol and methohexital sedation using an infusion pump Anesthesia Progress. ,vol. 43, pp. 9- 13 ,(1996)
Alice M. Arnold, Bruce M. Psaty, Lewis H. Kuller, Gregory L. Burke, Teri A. Manolio, Linda P. Fried, John A. Robbins, Richard A. Kronmal, Incidence of cardiovascular disease in older Americans: the cardiovascular health study. Journal of the American Geriatrics Society. ,vol. 53, pp. 211- 218 ,(2005) , 10.1111/J.1532-5415.2005.53105.X
Allan I. Pack, Dennis A. Silage, Donald D. Peterson, Alfred P. Fishman, Effects of aging on ventilatory and occlusion pressure responses to hypoxia and hypercapnia. The American review of respiratory disease. ,vol. 124, pp. 387- ,(2015) , 10.1164/ARRD.1981.124.4.387