Abdominal obesity and other risk factors largely explain the high CRP in indigenous Australians relative to the general population, but not gender differences: a cross-sectional study.

摘要: Background: Previous studies reported high C-reactive protein (CRP) levels in Indigenous Australians, which may contribute to their risk of cardiovascular disease. We compared CRP Australians and the general population, accounting for obesity other factors. Methods: Cross-sectional study factors (weight, height, waist hip circumferences, blood pressure, lipids, glucose, smoking status) population-based samples from Diabetes Related conditions Urban people Darwin region (DRUID) study, Australian Diabetes, Obesity Lifestyle (AusDiab) follow-up. Results: concentrations were higher women than men DRUID AusDiab. After multivariate adjustment, including circumference, odds (>3.0 mg/L) relative AusDiab no longer statistically significant, but elevated was still more likely men. adjusting BMI (instead circumference) participants among women, not Lower HDL cholesterol, impaired glucose tolerance (IGT), diastolic pressure associated with having a both while current women. Conclusions: High largely explained by factors, particular abdominal obesity. Irrespective its independence as factor, or aetiological association coronary heart disease (CHD), urban are reflect increased vascular metabolic risk. The significance should be investigated future longitudinal studies.