Incretin effect after oral amino acid ingestion in humans.
作者： Ola Lindgren , Giovanni Pacini , Andrea Tura , Jens J Holst , Carolyn F Deacon
DOI: 10.1210/JC.2014-3865
关键词:
摘要: Context: The incretin effect is the augmented insulin secretion by oral vs iv glucose at matching levels. We previously demonstrated an when fat given orally rather than iv, suggesting also after fat. However, whether present amino acid ingestion not known. Objective: objective of study was to explore and hormones administration matched total concentrations in healthy subjects. Design: An mixture (Vaminolac) administered or a rate resulting 12 male volunteers with age 22.5 ± 1.4 years body mass index 22.4 kg/m2, who had no history diabetes. Main Outcome Measures: outcome measures were area under 120-minute curve for insulin, C-peptide, glucagon, intact glucagon like peptide-1 (GLP-1) glucose-dependent insulinotropic polypepti...
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