The role of nutrition and epigenetics in environmental toxicology

作者: Abhishek Venkatratnam , Rebecca C. Fry

DOI: 10.1016/B978-0-12-819968-8.00013-5

关键词:

摘要: Abstract Variation in nutritional status is one of the many determinants health or disease with large implications for public health. As evidence impact diet, animal model research has shown that alterations can lead to increased risk diabetes, obesity, chronic diseases, context chemical exposures. In relation toxicologic responses exposures, detoxifying mechanisms associated exposures subsequently influencing effects. Nutrients also directly interact xenobiotics, thereby altering their toxicokinetics and This chapter provides a summary interaction between nutrition DNA methylation toxicants humans, rodents, vitro models.

参考文章(189)
Sharee A. Wiggins, Modern nutrition in health and disease Patient Education and Counseling. ,vol. 25, pp. 335- 336 ,(1995) , 10.1016/0738-3991(95)90004-7
S Lin, TC Thomas, LH Storlien, XF Huang, Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J mice. International Journal of Obesity. ,vol. 24, pp. 639- 646 ,(2000) , 10.1038/SJ.IJO.0801209
Russell F. Miller, Paul H. Phillips, The enhancement of the toxicity of sodium fluoride in the rat by high dietary fat. Journal of Nutrition. ,vol. 56, pp. 447- 454 ,(1955) , 10.1093/JN/56.4.447
Romilly E. Hodges, Deanna M. Minich, Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application Journal of Nutrition and Metabolism. ,vol. 2015, pp. 760689- 760689 ,(2015) , 10.1155/2015/760689
John N. Hathcock, Nutritional toxicology: basic principles and actual problems. Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment. ,vol. 7, ,(1990) , 10.1080/02652039009373836
Bruce R. Bistrian, Interaction between nutrition and inflammation in end-stage renal disease. Blood Purification. ,vol. 18, pp. 333- 336 ,(2000) , 10.1159/000014458
Rex J. Scaramuzzi, Bruce K. Campbell, Jeff A. Downing, Nigel R. Kendall, Muhammad Khalid, Minerva Muñoz-Gutiérrez, Anongnart Somchit, A review of the effects of supplementary nutrition in the ewe on the concentrations of reproductive and metabolic hormones and the mechanisms that regulate folliculogenesis and ovulation rate. Reproduction Nutrition Development. ,vol. 46, pp. 339- 354 ,(2006) , 10.1051/RND:2006016
Peter G. Welling, Influence of food and diet on gastrointestinal drug absorption: a review. Journal of Pharmacokinetics and Biopharmaceutics. ,vol. 5, pp. 291- 334 ,(1977) , 10.1007/BF01061694