The Role of Inflammation and Infection in Preterm Birth

作者: Jamie A. Bastek , Luis M. Gómez , Michal A. Elovitz

DOI: 10.1016/J.CLP.2011.06.003

关键词:

摘要: Much emphasis in recent decades has been devoted to inflammation and infection as a premier causal mechanism of preterm birth. This article explores the epidemiologic, clinical, animal data that exist support this conceptual paradigm well proposed mechanisms through which potentially mitigate adversity prematurity. Truly successful interventions are not likely occur until pathogenesis birth role causing only parturition but also fetal neonatal injury is fully elucidated.

参考文章(189)
Nan Okun, Karen A. Gronau, Mary E. Hannah, Antibiotics for bacterial vaginosis or Trichomonas vaginalis in pregnancy: a systematic review Obstetrics & Gynecology. ,vol. 105, pp. 857- 868 ,(2005) , 10.1097/01.AOG.0000157108.32059.8F
Alice R. Goepfert, Marjorie K. Jeffcoat, William W. Andrews, Ona Faye-Petersen, Suzanne P. Cliver, Robert L. Goldenberg, John C. Hauth, Periodontal disease and upper genital tract inflammation in early spontaneous preterm birth. Obstetrics & Gynecology. ,vol. 104, pp. 777- 783 ,(2004) , 10.1097/01.AOG.0000139836.47777.6D
Robert L Goldenberg, Jennifer F Culhane, Jay D Iams, Roberto Romero, Epidemiology and causes of preterm birth The Lancet. ,vol. 371, pp. 75- 84 ,(2008) , 10.1016/S0140-6736(08)60074-4
Martha Lappas, Michael Permezel, Harry M. Georgiou, Gregory E. Rice, Regulation of Phospholipase Isozymes by Nuclear Factor-κB in Human Gestational Tissues in Vitro The Journal of Clinical Endocrinology and Metabolism. ,vol. 89, pp. 2365- 2372 ,(2004) , 10.1210/JC.2003-031385
Peta L. Grigsby, Miles J. Novy, Kristina M. Adams Waldorf, Drew W. Sadowsky, Michael G. Gravett, Choriodecidual inflammation: a harbinger of the preterm labor syndrome. Reproductive Sciences. ,vol. 17, pp. 85- 94 ,(2010) , 10.1177/1933719109348025
Satoshi Kajikawa, Nobuhiko Kaga, Yoshihiro Futamura, Chihaya Kakinuma, Yasunori Shibutani, Lipoteichoic acid induces preterm delivery in mice. Journal of Pharmacological and Toxicological Methods. ,vol. 39, pp. 147- 154 ,(1998) , 10.1016/S1056-8719(98)00015-X
George A. Macones, Samuel Parry, Deborah B. Nelson, Jerome F. Strauss, Jack Ludmir, Arnold W. Cohen, David M. Stamilio, Dina Appleby, Bonnie Clothier, Mary D. Sammel, Marjorie Jeffcoat, Treatment of localized periodontal disease in pregnancy does not reduce the occurrence of preterm birth: results from the Periodontal Infections and Prematurity Study (PIPS) American Journal of Obstetrics and Gynecology. ,vol. 202, pp. 147- 149 ,(2010) , 10.1016/J.AJOG.2009.10.892
Emmet Hirsch, Yana Filipovich, Mala Mahendroo, Signaling via the type I IL-1 and TNF receptors is necessary for bacterially induced preterm labor in a murine model American Journal of Obstetrics and Gynecology. ,vol. 194, pp. 1334- 1340 ,(2006) , 10.1016/J.AJOG.2005.11.004
Rudolph P. Galask, Michael W. Varner, C. Rosemarie Petzold, Stephen L. Wilbur, Bacterial attachment to the chorioamniotic membranes. American Journal of Obstetrics and Gynecology. ,vol. 148, pp. 915- 928 ,(1984) , 10.1016/0002-9378(84)90534-9
Michal A Elovitz, Conjeevaram Mrinalini, Mary D Sammel, Elucidating the early signal transduction pathways leading to fetal brain injury in preterm birth. Pediatric Research. ,vol. 59, pp. 50- 55 ,(2006) , 10.1203/01.PDR.0000191141.21932.B6