Physiologic cholestasis: Elevation of the primary serum bile acid concentrations in normal infants
作者： Frederick J. Suchy , William F. Balistreri , James E. Heubi , John E. Searcy , Ron S. Levin
DOI: 10.1016/0016-5085(81)90078-0
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摘要: Abstract Immaturity of hepatic excretory function resulting in a period "physiologic cholestasis" may occur during early life. Serum bile acids should accurately reflect maturation the enterohepatic circulation; we therefore determined serum concentrations primary normal infants to define age-related changes. There was striking rise cholylglycine and conjugates chenodeoxycholate first few days life over levels detected cord sera; values attained were significantly greater than maximal postprandial found children 3 yr age (p
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