Allopregnanolone modulation of HPA axis function in the adult rat
作者： Giovanni Biggio , Maria Giuseppina Pisu , Francesca Biggio , Mariangela Serra
DOI: 10.1007/S00213-014-3521-6
关键词:
摘要: Rationale GABAergic neuronal circuits regulate neuroendocrine stress response, and the most potent positive endogenous modulator of GABAA receptor function is allopregnanolone. This neurosteroid acts in a nongenomic manner to selectively increase inhibitory signal meditated by receptors; addition, it also induces long-lasting changes expression specific subunits various brain regions, with consequent function.
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