A prognostic scoring system for patients with multiple hepatocellular carcinomas treated by hepatectomy.

摘要: The selection criteria of hepatectomy for patients with multiple hepatocellular carcinomas (HCCs) remain controversial. A scoring system based on preoperative data and independent predictors overall survival (OS) was developed in a primary cohort 510 who underwent HCCs from 1998 to 2006, validated 177 were operated 2006 2009 at the Eastern Hepatobiliary Surgery Hospital. In NDR system, tumor number (N) > 3, total diameter (D) > 8 cm, ratio largest/smallest (R) > 6 OS. Its predictive accuracy as determined by area under curve (AUC, 0.718) larger than four conventional staging systems (0.524–0.662). It stratified postoperative OS into five levels (0–4 score). 5-year rate score 0–2 46.5 % versus 13.9 % those > 2 (P < 0.001). Patients therefore recommended hepatectomy. feasibility this compared previously reported criteria. If two more stringent inclusion adopted, 45.5–75.7 % would be excluded, but their rates comparable those within (44.7 % vs. 52.1 %, P = 0.083; 46.6 % 46.3 %, P = 0.674). less used, an additional 25.9 % received hepatectomy, 13.9 %. accurate selecting