作者: Melanie Eger , Jamal Hussen , Caroline Drong , Ulrich Meyer , Dirk von Soosten
DOI: 10.1016/J.VETIMM.2015.04.007
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摘要: The peripartal period of dairy cows is associated with a higher incidence infectious diseases like mastitis or metritis, particularly in high-yielding animals. onset lactation induces negative energy balance and shift glucose distribution toward the udder. Glucose used as primary fuel by monocytes which give rise to macrophages, key cells defense against pathogens. aim this study was analyze whether animals high low body condition score (BCS) differ composition uptake capacities bovine monocyte subsets. Blood samples were taken from 27 starting 42 days before parturition until day 56 after parturition. allocated two groups according their BCS. A feeding regime applied, BCS group received amounts concentrate more restricted compared group, promote postpartal lipolysis enhance group. cell counts classical (cM), intermediate (intM) nonclassical (ncM) increased at 7 calving. In intM numbers significantly Within suffering metritis showed cM, ncM Classical similar while values for lower. Compared antepartal irrespective all subsets decreased conclusion, whereas capacity altered parturition, it not linked supply diseases.