作者: Federico Esposti , Jamie Johnston , Juliana M. Rosa , Kin-Mei Leung , Leon Lagnado
DOI: 10.1016/J.NEURON.2013.05.001
关键词:
摘要: Cross-modal regulation of visual performance by olfactory stimuli begins in the retina, where dopaminergic interneurons receive projections from bulb. However, we do not understand how alter processing signals within retina. We investigated this question in vivo imaging activity transgenic zebrafish expressing SyGCaMP2 bipolar cell terminals and GCaMP3.5 ganglion cells. The food-related amino acid methionine reduced gain increased sensitivity responses to luminance contrast transmitted through OFF cells but ON. effects stimulus were blocked inhibiting dopamine uptake release. Activation receptors synaptic transmission potentiated calcium currents isolated These results indicate that retina presynaptic channels control