Olfactory Stimulation Selectively Modulates the OFF Pathway in the Retina of Zebrafish

作者: Federico Esposti , Jamie Johnston , Juliana M. Rosa , Kin-Mei Leung , Leon Lagnado

DOI: 10.1016/J.NEURON.2013.05.001

关键词:

摘要: Cross-modal regulation of visual performance by olfactory stimuli begins in the retina, where dopaminergic interneurons receive projections from bulb. However, we do not understand how alter processing signals within retina. We investigated this question in vivo imaging activity transgenic zebrafish expressing SyGCaMP2 bipolar cell terminals and GCaMP3.5 ganglion cells. The food-related amino acid methionine reduced gain increased sensitivity responses to luminance contrast transmitted through OFF cells but ON. effects stimulus were blocked inhibiting dopamine uptake release. Activation receptors synaptic transmission potentiated calcium currents isolated These results indicate that retina presynaptic channels control

参考文章(61)
Johnny Karlsson, Jonas von Hofsten, Per-Erik Olsson, Generating transparent zebrafish: a refined method to improve detection of gene expression during embryonic development. Marine Biotechnology. ,vol. 3, pp. 522- 527 ,(2001) , 10.1007/S1012601-0053-4
Zheng-Shi Lin, Stephen Yazulla, Depletion of retinal dopamine increases brightness perception in goldfish. Visual Neuroscience. ,vol. 11, pp. 683- 693 ,(1994) , 10.1017/S0952523800002996
U. Behrens, H.-J. Wagner, Terminal nerve and vision. Microscopy Research and Technique. ,vol. 65, pp. 25- 32 ,(2004) , 10.1002/JEMT.20108
Tom Baden, Federico Esposti, Anton Nikolaev, Leon Lagnado, Spikes in Retinal Bipolar Cells Phase-Lock to Visual Stimuli with Millisecond Precision Current Biology. ,vol. 21, pp. 1859- 1869 ,(2011) , 10.1016/J.CUB.2011.09.042
Alan D. Springer, Centrifugal innervation of goldfish retina from ganglion cells of the nervus terminalis The Journal of Comparative Neurology. ,vol. 214, pp. 404- 415 ,(1983) , 10.1002/CNE.902140405
Peter H. Schiller, Julie H. Sandell, John H. R. Maunsell, Functions of the ON and OFF channels of the visual system. Nature. ,vol. 322, pp. 824- 825 ,(1986) , 10.1038/322824A0
Andrew G. Knapp, John E. Dowling, Dopamine enhances excitatory amino acid-gated conductances in cultured retinal horizontal cells Nature. ,vol. 325, pp. 437- 439 ,(1987) , 10.1038/325437A0
Naoyuki Yamamoto, Hironobu Ito, Afferent sources to the ganglion of the terminal nerve in teleosts. The Journal of Comparative Neurology. ,vol. 428, pp. 355- 375 ,(2000) , 10.1002/1096-9861(20001211)428:2<355::AID-CNE12>3.0.CO;2-W
Qing Bai, Jessica A. Garver, Neil A. Hukriede, Edward A. Burton, Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene Nucleic Acids Research. ,vol. 35, pp. 6501- 6516 ,(2007) , 10.1093/NAR/GKM608
A. Feigenspan, J. Bormann, Facilitation of GABAergic signaling in the retina by receptors stimulating adenylate cyclase. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 10893- 10897 ,(1994) , 10.1073/PNAS.91.23.10893